Frauenheilkunde up2date, Table of Contents Frauenheilkunde up2date 2011; 5(5): 309-318DOI: 10.1055/s-0031-1283748 Gynäkologische Endokrinologie und Reproduktionsmedizin © Georg Thieme Verlag KG Stuttgart · New YorkDas PCO-Syndrom – aktuelle Aspekte für die Praxis R. Seufert , R. Gomez , C. Skala , M. SchorschRecommend Article Abstract Buy Article All articles of this category Full Text References Literatur 1 Stein IF, Leventhal ML. Amenorrhea associated with bilateral Polycycsic Ovaries. Am J Obstet Gynecol 1935; 29: 181-191 2 Rotterdam ESHRE / ASRM – Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and longterm health risks releated to polycystic ovary syndrome. Fert Steril 2004; 81: 19 3 Yen SS, Vela P, Rankin J. Inappropriate secretion of follicle-stimulating hormone and luteinizing hormone in polycyctic ovarian disease. J Clin Endocrinol Metab 1970; 30: 435 4 Diamanti-Kandarakis E, Kandarakis H, Legro RS. The role of genes and environment in the etiology of PCOS. Endocrine 2006; 30: 19 5 Franks S. Polycystic ovary syndrome. N Engl J Med 1995; 333: 853 6 Azziz R, Sanchez LA, Knochenhauer ES et al. Androgen excess in women: experience with over 1000 consecutive patients. J Clin Endocrinol Metab 2004; 89: 453 7 Costello MF, Shrestha B, Eden J et al. Metformin versus oral contraceptive pills in polycyctic ovary syndrome: a Cochrane review. Hum Reprod 2007; 22: 1200 8 Evans DJ, Burkow CW. Spironolactone in the treatment of idiopathic hirsutism and the polycystic ovary syndrome. J Roy Soc Med 1986; 79: 453 9 Grunwald K, Rabe T, Schöereth G et al. Serumhormone vor und unter Therapie mit Cyproteronacetat und Spironolacton bei Patientinnen mit Androgensierungserscheinungen. Geburtsh Frauenheilkd 1994; 54: 634 10 Calaf J, Lopez E, Millet A et al. Long-term efficacy and tolerability of flutamide combined with oral contraception in moderate to severe hirsutism. J Clin Endocrinol Metab 2007; 92: 3446 11 Palomba S, Orio F, Falbo A et al. Prospective parallel randomized,double-blind double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome. J Clin Endocrinol Metabol 2005; 90: 4068 12 Legro RS, Barnhart HX, Schlaff WD et al. Cooperatative Multicenter Reproductive Medicine Network. Clomiphene, metformin or both for infertility in the polycystic ovary syndrome. N Engl J Med 2007; 356: 551 13 Kashyap S, Wells G, Rosenwaks Z. Insulin-Sensitizing agents as primary therapy for patients with PCOS. Hum Reprod 2004; 19: 2474-2483